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Phospho-AKT1 (Thr450) Rabbit mAb

Anti-Phospho-AKT1 (Thr450) Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263148

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263148
Product Name:   Anti-Phospho-AKT1 (Thr450) Rabbit Monoclonal Antibody
Synonyms:   AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha
UNIPROT ID:   P31749
Background:    Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Thr450 of human AKT1
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-4A7
MW:    Calculated MW: 56 kDa; Observed MW: 56 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-AKT1 (Thr450) in U2OS, C6 lysates using Phospho-AKT1 (Thr450) antibody.
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