NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N225327 | ||||
Product Name: Anti-Phospho-ALK (Tyr1604) Rabbit pAb | ||||
Synonyms: ALK; ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD antigen CD246 | ||||
UNIPROT ID: Q9UM73 | ||||
Background: Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. | ||||
Immunogen: Synthetic peptide of human ALK | ||||
Applications: WB,IHC-P,ICC/IF | ||||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Clone ID: – | ||||
MW: Calculated MW: 176 kDa; Observed MW: 176 kDa | ||||
Isotype: IgG | ||||
Purification: Affinity Purified | ||||
Species Reactivity: Human | ||||
Conjugation: Unconjugated | ||||
Modification: Phosphorylated | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
Research Areas: Tags & Cell Markers | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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