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Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Rabbit mAb

Anti-Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262190

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262190
Product Name:   Anti-Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Rabbit Monoclonal Antibody
Synonyms:   MAPK1/MAPK3
UNIPROT ID:   P27361/P28482
Background:    Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Thr202/Tyr204 of human Erk1
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-9E9
MW:    Calculated MW: 44,42 kDa; Observed MW: 44,42 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    NeuroscienceyyyyyPrion disease
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Erk1 (pT202/pY204)/Erk2 (pT185/pY187) in C6, Hela lysates using Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) antibody.
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