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Phospho-GSK3 (Tyr279/Tyr216) Rabbit pAb

Anti-Phospho-GSK3 (Tyr279/Tyr216) Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225306

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225306
Product Name:   Anti-Phospho-GSK3 (Tyr279/Tyr216) Rabbit pAb
Synonyms:   Serine/threonine-protein kinase GSK3A
UNIPROT ID:   P49840
Background:    GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
Immunogen:    Synthetic peptide of human GSK3A
Applications:    WB,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 51 kDa; Observed MW: 46,51 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using Phospho-GSK3 (Tyr279/Tyr216) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Western blot analysis of Phospho-GSK3 (Tyr279/Tyr216) in 293 lysates using Phospho-GSK3 alpha/beta (Tyr279/Tyr216) antibody.

Immunofluorescence analysis of Phospho-GSK3 (Tyr279/Tyr216) in Hela cells using GSK3a/b(Phospho-Tyr279/216) antibody(red).
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