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Phospho-IGF1 Receptor (Tyr1166) Rabbit mAb

Anti-Phospho-IGF1 Receptor (Tyr1166) Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262412

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262412
Product Name:   Anti-Phospho-IGF1 Receptor (Tyr1166) Rabbit Monoclonal Antibody
Synonyms:   IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
UNIPROT ID:   P08069
Background:    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human INSR/IGF-1R
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R06-6B1
MW:    Calculated MW: 155 kDa; Observed MW: 95 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-IGF1R (Tyr1166) in C6, 3T3, Hela lysates using Phospho-IGF1 Receptor (Tyr1166) antibody.
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