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Phospho-IRS1 (Ser636) Rabbit pAb

Anti-Phospho-IRS1 (Ser636) Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225022

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225022
Product Name:   Anti-Phospho-IRS1 (Ser636) Rabbit pAb
Synonyms:   IRS1; Insulin receptor substrate 1; IRS-1
UNIPROT ID:   P35568
Background:    May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .
Immunogen:    The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser636. AA range:603-652
Applications:    WB,IHC-F,IHC-P,ICC/IF,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 132 kDa; Observed MW: 150 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Tags & Cell Markers
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human brain using Phospho-IRS1 (Ser636) antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Western blot analysis of Phospho-IRS1 (Ser636) in SH-SY5Y lysates using Phospho-IRS1 (S636) antibody.
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