Email: info@neweastbio.com   |  Call: 6109452007

Phospho-IRS1 (Ser639) Rabbit pAb

Anti-Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225416

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225416
Product Name:   Anti-Phospho-IRS1 (Ser639) Rabbit pAb
Synonyms:   IRS1; Insulin receptor substrate 1; IRS-1
UNIPROT ID:   P35568
Background:    May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .
Immunogen:    The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser639. AA range:605-654
Applications:    WB,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 132 kDa; Observed MW: 150 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Tags & Cell Markers
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma, using IRS1 (Phospho-Ser639) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Western blot analysis of Phospho-IRS1 (Ser639) in various lysates using Phospho-IRS1 (Ser639) antibody.
          Publications