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Phospho-RSK1 p90 (Thr359/Ser363) Rabbit pAb

Anti-Phospho-RSK1 p90 (Thr359/Ser363) Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225595

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225595
Product Name:   Anti-Phospho-RSK1 p90 (Thr359/Ser363) Rabbit pAb
Synonyms:   RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP
UNIPROT ID:   Q15418
Background:    Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.
Immunogen:    A synthesized peptide derived from human Phospho-RSK1 p90 (T359+S363)
Applications:    WB,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 83 kDa; Observed MW: 90 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of RSK 1 p90 Phosphorylation in K562 lysates treated with EGF using Phospho-RSK1 p90 (Thr359/Ser363) antibody.
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