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Phospho-Src (Tyr419) Rabbit pAb

Anti-Phospho-Src (Tyr419) Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225623

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225623
Product Name:   Anti-Phospho-Src (Tyr419) Rabbit pAb
Synonyms:   SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src
UNIPROT ID:   P12931
Background:    Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).
Immunogen:    A synthesized peptide derived from human Phospho-Src (Y419)
Applications:    WB,FC
Recommended Dilutions:    WB: 1/500-1/1000 FC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 60 kDa; Observed MW: 60 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-Src (Y419) in A431 lysates treated with pervanadate using Phospho-Src (Tyr419) antibody.
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