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PI3 Kinase p85 alpha (3H5) Mouse mAb

Anti-PI3 Kinase p85 alpha (3H5) Mouse Monoclonal Antibody
5/5

$349.00

Cat.#:  N261374

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261374
Product Name:   Anti-PI3 Kinase p85 alpha (3H5) Mouse Monoclonal Antibody
Synonyms:   PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
UNIPROT ID:   P27986
Background:    Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Immunogen:    Purified recombinant protein expressed in E.coli.
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    3H5-1H4-9D2
MW:    Calculated MW: 84 kDa; Observed MW: 84 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemical analysis of paraffin-embedded Human tonsils using PI3 Kinase p85 alpha (3H5) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded rat Liver Tissue using PI3 Kinase p85 alpha (3H5) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of PI3 Kinase p85 alpha (3H5) in THP-1, MCF-7, Goat Muscle, CHO-K1, C6, 3T3 lysates using PI3 Kinase p85 alpha (3H5) antibody

Western blot analysis of PI3 Kinase p85 alpha (3H5) in Hela, A549, HL-60, U2OS, C6 lysates using PI3 Kinase p85 alpha (3H5) antibody.
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