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PI3 Kinase p85 alpha Rabbit mAb

Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261654

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261654
Product Name:   Anti-PI3 Kinase p85 alpha Rabbit Monoclonal Antibody
Synonyms:   PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
UNIPROT ID:   P27986
Background:    Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Immunogen:    A synthetic peptide of human PI 3 Kinase p85 alpha
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-3C7
MW:    Calculated MW: 84 kDa; Observed MW: 84 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat,Hamster
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Hypoxia Signal Transductionyyyyy Hypoxia-induced
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of PI3 Kinase p85 alpha (green) in MCF-7 using PI3 Kinase p85 alpha antibody,and DAPI(blue)

Western blot analysis of PI3 Kinase p85 alpha in Jurkat, C6, CHO-K1 lysates using PI3 Kinase p85 alpha antibody.
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