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PIP5K1B Rabbit pAb

Anti-PIP5K1B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217159

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217159
Product Name:   Anti-PIP5K1B Rabbit Polyclonal Antibody
Synonyms:   MSS4; STM7
UNIPROT ID:   O14986 (Gene Accession – BC030587 )
Background:    Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization. The PIPK family is divided into type I, type II and type III . Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting . The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I †, ?, and ?, which are characterized by phosphorylating PI4P on the 5-hydroxyl . PIPK I † (designated PIPK I ? in mouse) is expressed in brain tissue . PIPK I ?, designated PIPK I a in mouse, is also called STM7. PIPK I ? has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys.
Immunogen:    Fusion protein of human PIP5K1B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217159(PIP5K1B Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217159(Anti-PIP5K1B Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 217159(Anti-PIP5K1B Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D221896(Anti-PIP5K1B Antibody) at dilution 1/30.
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