NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N261197 | ||||
Product Name: Anti-Placental Alkaline Phosphatase Mouse Monoclonal Antibody | ||||
Synonyms: ALPP; PLAP; Alkaline phosphatase; placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1 | ||||
UNIPROT ID: P05187 | ||||
Background: PLAP may assist in guiding migratory cells and transporting specific molecules, such as fatty acids and immunoglobulins, across the plasma membrane. The three tissue-specific APs identified in human, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous and their genes are clustered on chromosome 2q. | ||||
Immunogen: Purified recombinant fragment of human ALPP expressed in E. Coli. | ||||
Applications: WB,IHC-P | ||||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 | ||||
Host Species: Mouse | ||||
Clonality: Mouse Monoclonal | ||||
Clone ID: 3C11-E7-A1 | ||||
MW: Calculated MW: 58 kDa; Observed MW: 70 kDa | ||||
Isotype: IgG2b | ||||
Purification: Ascitic Fluid | ||||
Species Reactivity: Human | ||||
Conjugation: Unconjugated | ||||
Modification: Unmodified | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
Research Areas: Tags & Cell Markers | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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