Email: info@neweastbio.com   |  Call: 6109452007

PLK1 Rabbit pAb

Anti-PLK1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217122

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217122
Product Name:   Anti-PLK1 Rabbit Polyclonal Antibody
Synonyms:   PLK; STPK13
UNIPROT ID:   P53350 (Gene Accession – BC002369 )
Background:    Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13 (STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase 1) gene. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.
Immunogen:    Fusion protein of human PLK1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 15-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 217122(PLK1 Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 217122(Anti-PLK1 Antibody) at dilution 1/15.
          Publications