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PRAME Rabbit pAb

Anti-PRAME Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217712

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217712
Product Name:   Anti-PRAME Rabbit Polyclonal Antibody
Synonyms:   MAPE; OIP4; CT130; OIP-4
UNIPROT ID:   P78395 (Gene Accession – BC014074 )
Background:    This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human PRAME
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human esophagus cancer tissue using 217712(PRAME Antibody) at a dilution of 1/50(Cell membrane).
          Publications