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PRKAA1 Rabbit pAb

Anti-PRKAA1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S214064

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S214064
Product Name:   Anti-PRKAA1 Rabbit Polyclonal Antibody
Synonyms:   AMPK; AMPKa1
UNIPROT ID:   Q13131 (Gene Accession – NP_006242 )
Background:    The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5′-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Immunogen:    Synthetic peptide of human PRKAA1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Metabolism, Cardiovascular, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 214064(PRKAA1 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 214064(Anti-PRKAA1 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 214064(Anti-PRKAA1 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D161273(Anti-PRKAA1 Antibody) at dilution 1/70.
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