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PRKAR1B Rabbit pAb

Anti-PRKAR1B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220173

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220173
Product Name:   Anti-PRKAR1B Rabbit Polyclonal Antibody
Synonyms:   PRKAR1
UNIPROT ID:   P31321 (Gene Accession – NP_001158230 )
Background:    Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.
Immunogen:    Synthetic peptide of human PRKAR1B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 220173(PRKAR1B Antibody) at a dilution of 1/60(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 220173(Anti-PRKAR1B Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220173(Anti-PRKAR1B Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D261081(Anti-PRKAR1B Antibody) at dilution 1/60.
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