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PRKN Rabbit pAb

Anti-PRKN Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222394

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222394
Product Name:   Anti-PRKN Rabbit Polyclonal Antibody
Synonyms:   PDJ; AR-JP; LPRS2; PARK2
UNIPROT ID:   O60260 (Gene Accession – NP_004553 )
Background:    The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
Immunogen:    Synthetic peptide of human PRKN
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience, Cell Biology, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 222394(PRKN Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 222394(Anti-PRKN Antibody) at dilution 1/50.
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