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PROM1 Rabbit pAb

Anti-PROM1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220352

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220352
Product Name:   Anti-PROM1 Rabbit Polyclonal Antibody
Synonyms:   RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
UNIPROT ID:   O43490 (Gene Accession – NP_001139319 )
Background:    This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human PROM1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 220352(PROM1 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 220352(Anti-PROM1 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220352(Anti-PROM1 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D261406(Anti-PROM1 Antibody) at dilution 1/70.
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