NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N262772 |
Product Name: Anti-PRPF8 Rabbit Monoclonal Antibody |
Synonyms: HPRP8; p220; PRP8; PRPC8; Prpf8; RP13; SNRNP220 |
UNIPROT ID: Q6P2Q9 |
Background: Central component of the spliceosome, which may play a role in aligning the pre-mRNA 5′- and 3′-exons for ligation. Interacts with U5 snRNA, and with pre-mRNA 5′-splice sites in B spliceosomes and 3′-splice sites in C spliceosomes. |
Immunogen: A synthetic peptide of human PRPF8 |
Applications: WB,IHC-P |
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 |
Host Species: Rabbit |
Clonality: Rabbit Monoclonal |
Clone ID: R06-1I7 |
MW: Calculated MW: 274 kDa; Observed MW: 274 kDa |
Isotype: IgG |
Purification: Affinity Purified |
Species Reactivity: Human |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Epigenetics and Nuclear Signaling |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of PRPF8 in Jurkat, Raji lysates using PRPF8 antibody. |