Email: info@neweastbio.com   |  Call: 6109452007

PSMB5 Rabbit pAb

Anti-PSMB5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219587

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219587
Product Name:   Anti-PSMB5 Rabbit Polyclonal Antibody
Synonyms:   MB1; LMPX
UNIPROT ID:   P28074 (Gene Accession – BC057840 )
Background:    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human PSMB5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 219587(PSMB5 Antibody) at a dilution of 1/55(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 219587(Anti-PSMB5 Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 219587(Anti-PSMB5 Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D227861(Anti-PSMB5 Antibody) at dilution 1/55.
          Publications