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PTCH1 Rabbit pAb

Anti-PTCH1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225484

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225484
Product Name:   Anti-PTCH1 Rabbit pAb
Synonyms:   PTCH1; PTCH; Protein patched homolog 1; PTC; PTC1
UNIPROT ID:   Q13635
Background:    This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
Immunogen:    The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50
Applications:    WB,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 161 kDa; Observed MW: 161 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemical analysis of paraffin-embedded Human tonsils using PTCH1 antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human testis using PTCH1 antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human testis using PTCH1 antibody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human Right kidney using PTCH1 antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human Right kidney using PTCH1 antibody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.
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