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PTGDR2 Rabbit pAb

Anti-PTGDR2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222120

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222120
Product Name:   Anti-PTGDR2 Rabbit Polyclonal Antibody
Synonyms:   DP2; DL1R; CD294; CRTH2; GPR44
UNIPROT ID:   Q9Y5Y4 (Gene Accession – NP_004769 )
Background:    This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3′ UTR of this gene have been associated with asthma susceptibility.
Immunogen:    Synthetic peptide of human PTGDR2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 20-100;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 222120(PTGDR2 Antibody) at a dilution of 1/35(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 222120(Anti-PTGDR2 Antibody) at dilution 1/35.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Human heart tissue lysate;
Primary antibody: 222120(PTGDR2 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 30 seconds
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