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PTGDS Rabbit pAb

Anti-PTGDS Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216756

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216756
Product Name:   Anti-PTGDS Rabbit Polyclonal Antibody
Synonyms:   PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS
UNIPROT ID:   P41222 (Gene Accession – BC005939 )
Background:    The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
Immunogen:    Fusion protein of human PTGDS
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-300;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 216756(PTGDS Antibody) at a dilution of 1/120(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 216756(Anti-PTGDS Antibody) at dilution 1/120.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 216756(Anti-PTGDS Antibody) at a dilution of 1/120.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D221182(Anti-PTGDS Antibody) at dilution 1/120.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse eye tissue lysate;
Primary antibody: 216756(PTGDS Antibody) at dilution 1/1300;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
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