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PTGS2 Rabbit pAb

Anti-PTGS2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217795

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217795
Product Name:   Anti-PTGS2 Rabbit Polyclonal Antibody
Synonyms:   COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
UNIPROT ID:   P35354 (Gene Accession – BC013734 )
Background:    Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Immunogen:    Fusion protein of human PTGS2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Metabolism, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 217795(PTGS2 Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 217795(Anti-PTGS2 Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 217795(Anti-PTGS2 Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D223097(Anti-PTGS2 Antibody) at dilution 1/55.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: SKOV3, LOVO and Hela cell lysates;
Primary antibody: 217795(PTGS2 Antibody) at dilution 1/600;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 40 seconds
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