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PTPRS Rabbit pAb

Anti-PTPRS Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219196

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219196
Product Name:   Anti-PTPRS Rabbit Polyclonal Antibody
Synonyms:   R-PTP-S; PTPSIGMA; R-PTP-sigma
UNIPROT ID:   Q13332 (Gene Accession – BC029496 )
Background:    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
Immunogen:    Fusion protein of human PTPRS
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219196(PTPRS Antibody) at a dilution of 1/110(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219196(Anti-PTPRS Antibody) at dilution 1/110.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 219196(Anti-PTPRS Antibody) at a dilution of 1/110.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D226035(Anti-PTPRS Antibody) at dilution 1/110.
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