Email: info@neweastbio.com   |  Call: 6109452007

PYK2 (4B4) Mouse mAb

Anti-PYK2 (4B4) Mouse Monoclonal Antibody
5/5

$349.00

Cat.#:  N261186

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261186
Product Name:   Anti-PYK2 (4B4) Mouse Monoclonal Antibody
Synonyms:   PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
UNIPROT ID:   Q14289
Background:    PYK2 a nonreceptor tyrosine kinase of the Fak family. Predominantly expressed in the cells derived from hematopoietic lineages and in the central nervous system. PYK2 is one of the signaling mediators for G-protein-coupled receptors. Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. Interacts with the SH2 domain of Grb2.
Immunogen:    Purified recombinant fragment of PYK2 (aa815-997) expressed in E. Coli.
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    4B4-D0-F3
MW:    Calculated MW: 116 kDa; Observed MW: 116 kDa
Isotype:    IgG2a
Purification:    Ascitic Fluid
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human Tonsil tissues using PYK2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Pyk2 in A549, Ramos, Jurkat, THP-1 and Raji lysates using Pyk2 antibody.
          Publications