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QK1 Rabbit mAb

Anti-QK1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262791

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262791
Product Name:   Anti-QK1 Rabbit Monoclonal Antibody
Synonyms:   QK; Hqk; QK1; QK3; hqkI
UNIPROT ID:   Q96PU8
Background:    RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5′-NACUAAY-N(1,20)-UAAY-3′ RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor .
Immunogen:    A synthetic peptide of human QK1
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R01-3F7
MW:    Calculated MW: 38 kDa; Observed MW: 38 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of QK1 in K562 lysates using QK1 antibody.

Western blot analysis of QK1 in 3T3, rat brain lysates using QK1 antibody.
          Publications