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RAPGEF1 Rabbit pAb

Anti-RAPGEF1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222143

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222143
Product Name:   Anti-RAPGEF1 Rabbit Polyclonal Antibody
Synonyms:   C3G; GRF2
UNIPROT ID:   Q13905 (Gene Accession – NP_005303 )
Background:    This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Immunogen:    Synthetic peptide of human RAPGEF1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 222143(RAPGEF1 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 222143(Anti-RAPGEF1 Antibody) at dilution 1/45.
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