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Rb Rabbit mAb

Anti-Rb Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262823

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262823
Product Name:   Anti-Rb Rabbit Monoclonal Antibody
Synonyms:   RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
UNIPROT ID:   P06400
Background:    Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.
Immunogen:    A synthetic peptide of human Rb
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R09-4H8
MW:    Calculated MW: 106 kDa; Observed MW: 110 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Rb(green) in Hela using Rb antibody,and DAPI(blue)

Western blot analysis of Rb in 3T3 lysates using Rb antibody.
          Publications