Email: info@neweastbio.com   |  Call: 6109452007

Rb Rabbit pAb

Anti-Rb Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225400

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225400
Product Name:   Anti-Rb Rabbit pAb
Synonyms:   RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
UNIPROT ID:   P06400
Background:    Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.
Immunogen:    The antiserum was produced against synthesized peptide derived from human Retinoblastoma. AA range:751-800
Applications:    WB,IHC-F,IHC-P,ICC/IF,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 106 kDa; Observed MW: 106 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Rb in COS7 and C6 lysates using Rb antibody.
          Publications