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RBM38 Rabbit pAb

Anti-RBM38 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220849

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220849
Product Name:   Anti-RBM38 Rabbit Polyclonal Antibody
Synonyms:   RNPC1; SEB4B; SEB4D; HSRNASEB; dJ800J21.2
UNIPROT ID:   Q9H0Z9 (Gene Accession – NP_059965 )
Background:    RBM38 is a cell cycle protein found in the cytosol and the nucleus that exists as two alternatively spliced isoforms, 1 (RNPC1a) and 2 (RNPC1b), of 239 and 121 amino acids, respectively. Independent of p53 expression, RBM38 isoform 1 induces cell cycle arrest in G1 phase through maintaining transcript stability at the 3?-UTR of p21, a regulator of cell cycle progression at S phase. RBM38 is also an mRNA splicing factor that regulates the expression of FGFR2. RBM38 contains one RRM (RNA recognition motif) domain.
Immunogen:    Synthetic peptide of human RBM38
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer, Stem Cells, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 220849(RBM38 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 220849(Anti-RBM38 Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 220849(Anti-RBM38 Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D262114(Anti-RBM38 Antibody) at dilution 1/45.
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