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RGS2 Rabbit pAb

Anti-RGS2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216764

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216764
Product Name:   Anti-RGS2 Rabbit Polyclonal Antibody
Synonyms:   G0S8
UNIPROT ID:   P41220 (Gene Accession – BC007049 )
Background:    Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
Immunogen:    Fusion protein of human RGS2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-200;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 216764(RGS2 Antibody) at a dilution of 1/95(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 216764(Anti-RGS2 Antibody) at dilution 1/95.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 216764(Anti-RGS2 Antibody) at a dilution of 1/95.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D221197(Anti-RGS2 Antibody) at dilution 1/95.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: A549 and A172 cell lysates;
Primary antibody: 216764(RGS2 Antibody) at dilution 1/1350;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds
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