NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S217759 | ||||
Product Name: Anti-RGS22 Rabbit Polyclonal Antibody | ||||
Synonyms: CT145; PRTD-NY2 | ||||
UNIPROT ID: Q8NE09 (Gene Accession – BC047060 ) | ||||
Background: RGS22 (regulator of G-protein signaling 22), also known as FLJ75004, PRTD-NY2, FLJ40080, MGC102908 or DKFZp434I092, is a novel 1264 amino acid regulator of G-protein signaling specific to to testis. RGS22 inhibits signal transduction and contains two isoforms as a result of alternative splicing. RGS22 is found in spermatogenic cells and Leydig cells, and may be involved in the translocation of GNA13 from the cytoplasm to the nucleus during spermiogenesis. RGS22 contains two RGS domains: RGS1 and RGS2, and the gene encoding RGS22 maps to human chromosome 8q22.2. | ||||
Immunogen: Fusion protein of human RGS22 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: 25-100; ELISA: 2000-5000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Signal Transduction | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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