Email: info@neweastbio.com   |  Call: 6109452007

RGS6 Rabbit pAb

Anti-RGS6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217757

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217757
Product Name:   Anti-RGS6 Rabbit Polyclonal Antibody
Synonyms:   GAP; S914; HA117
UNIPROT ID:   P49758 (Gene Accession – BC113572 )
Background:    This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.
Immunogen:    Fusion protein of human RGS6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 200-400; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 217757(RGS6 Antibody) at a dilution of 1/200(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 217757(Anti-RGS6 Antibody) at dilution 1/200.
          Publications