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RHOBTB2 Rabbit pAb

Anti-RHOBTB2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220495

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220495
Product Name:   Anti-RHOBTB2 Rabbit Polyclonal Antibody
Synonyms:   DBC2
UNIPROT ID:   Q9BYZ6 (Gene Accession – NP_055993 )
Background:    The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human RHOBTB2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220495(RHOBTB2 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220495(Anti-RHOBTB2 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 220495(Anti-RHOBTB2 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D261608(Anti-RHOBTB2 Antibody) at dilution 1/30.
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