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RITA1 Rabbit pAb

Anti-RITA1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219308

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219308
Product Name:   Anti-RITA1 Rabbit Polyclonal Antibody
Synonyms:   RITA; C12orf52
UNIPROT ID:   Q96K30 (Gene Accession – BC022092 )
Background:    Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Immunogen:    Fusion protein of human RITA1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 219308(RITA1 Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 219308(Anti-RITA1 Antibody) at dilution 1/60.
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