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RNF111 Rabbit pAb

Anti-RNF111 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218804

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218804
Product Name:   Anti-RNF111 Rabbit Polyclonal Antibody
Synonyms:   ARK; hRNF111
UNIPROT ID:   Q6ZNA4 (Gene Accession – BC010369 )
Background:    The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Immunogen:    Fusion protein of human RNF111
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human gastric cancer tissue using 218804(RNF111 Antibody) at a dilution of 1/50(Cytoplasm and Cell membrane).

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using 218804(Anti-RNF111 Antibody) at a dilution of 1/50.
          Publications