Email: info@neweastbio.com   |  Call: 6109452007

RNF7 Rabbit pAb

Anti-RNF7 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S211500

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S211500
Product Name:   Anti-RNF7 Rabbit Polyclonal Antibody
Synonyms:   SAG; ROC2; rbx2; CKBBP1
UNIPROT ID:   Q9UBF6 (Gene Accession – BC005966 )
Background:    The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Immunogen:    Fusion protein of human RNF7
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Metabolism, Cancer, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 211500(RNF7 Antibody) at a dilution of 1/80(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 211500(Anti-RNF7 Antibody) at dilution 1/80.
          Publications