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RPS6KA1 Rabbit pAb

Anti-RPS6KA1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217785

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217785
Product Name:   Anti-RPS6KA1 Rabbit Polyclonal Antibody
Synonyms:   RSK; HU-1; RSK1; MAPKAPK1A
UNIPROT ID:   Q15418 (Gene Accession – BC014966 )
Background:    This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen:    Fusion protein of human RPS6KA1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 30-150;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217785(RPS6KA1 Antibody) at a dilution of 1/45(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217785(Anti-RPS6KA1 Antibody) at dilution 1/45.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: 231 cells;
Primary antibody: 217785(RPS6KA1 Antibody) at dilution 1/800;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 30 seconds
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