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RPS6KB1 Rabbit pAb

Anti-RPS6KB1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216706

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216706
Product Name:   Anti-RPS6KB1 Rabbit Polyclonal Antibody
Synonyms:   S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha
UNIPROT ID:   P23443 (Gene Accession – BC053365 )
Background:    This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Immunogen:    Fusion protein of human RPS6KB1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Metabolism, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human gastric cancer tissue using 216706(RPS6KB1 Antibody) at a dilution of 1/25(Cytoplasm or Nucleus).

Immunohistochemistry analysis of paraffin-embedded Human bladder cancer tissue using 216706(Anti-RPS6KB1 Antibody) at a dilution of 1/25.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: Jurkat, 293T, Hela, Mouse liver tissue lysates;
Primary antibody: 216706(RPS6KB1 Antibody) at dilution 1/200;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
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