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RRAD Rabbit pAb

Anti-RRAD Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220186

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220186
Product Name:   Anti-RRAD Rabbit Polyclonal Antibody
Synonyms:   RAD; RAD1; REM3
UNIPROT ID:   P55042 (Gene Accession – NP_004156.1 )
Background:    The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.
Immunogen:    Synthetic peptide of human RRAD
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 220186(RRAD Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 220186(Anti-RRAD Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 220186(Anti-RRAD Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with synthetic peptide and then with D261101(Anti-RRAD Antibody) at dilution 1/50.
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