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RYK Rabbit mAb

Anti-RYK Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263113

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263113
Product Name:   Anti-RYK Rabbit Monoclonal Antibody
Synonyms:   ERK 3; JTK5; JTK5A; Ryk; RYK1; Vik
UNIPROT ID:   P34925
Background:    May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Immunogen:    A synthetic peptide of human RYK
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-4E1
MW:    Calculated MW: 68 kDa; Observed MW: 72 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:   
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using RYK antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of RYK in Hela, A549, HL-60, U2OS, U87-MG lysates using RYK antibody.

Immunocytochemistry analysis of RYK (green) in hela using RYK antibody,and DAPI(blue)
          Publications