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S100A4 Rabbit pAb

Anti-S100A4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213950

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213950
Product Name:   Anti-S100A4 Rabbit Polyclonal Antibody
Synonyms:   42A, 18A2, CAPL, FSP1, MTS1, P9KA, PEL98
UNIPROT ID:   P26447 (Gene Accession – NP_002952 )
Background:    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Immunogen:    Synthetic peptide of human S100A4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 213950(S100A4 Antibody) at a dilution of 1/80(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 213950(Anti-S100A4 Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 213950(Anti-S100A4 Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D161103(Anti-S100A4 Antibody) at dilution 1/80.
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