Email: info@neweastbio.com   |  Call: 6109452007

SASH1 Rabbit pAb

Anti-SASH1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S214648

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S214648
Product Name:   Anti-SASH1 Rabbit Polyclonal Antibody
Synonyms:   SH3D6A; dJ323M4.1
UNIPROT ID:   O94885 (Gene Accession – NP_056093 )
Background:    This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients.
Immunogen:    Synthetic peptide of human SASH1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 30-150;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 214648(SASH1 Antibody) at a dilution of 1/30(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 214648(Anti-SASH1 Antibody) at dilution 1/30.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: Human urinary bladder tissue lysate;
Primary antibody: 214648(SASH1 Antibody) at dilution 1/300;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
          Publications