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SATB1 Rabbit mAb

Anti-SATB1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263112

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263112
Product Name:   Anti-SATB1 Rabbit Monoclonal Antibody
Synonyms:   DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1)
UNIPROT ID:   Q01826
Background:    SATB1 is a crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling.
Immunogen:    A synthetic peptide of human SATB1
Applications:    WB,IHC-P,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-5H7
MW:    Calculated MW: 86 kDa; Observed MW: 100 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human tonsil using SATB1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of SATB1 in Hela, A549, HL-60, U2OS lysates using SATB1 antibody.
          Publications