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SCN1B Rabbit pAb

Anti-SCN1B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220882

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220882
Product Name:   Anti-SCN1B Rabbit Polyclonal Antibody
Synonyms:   ATFB13; BRGDA5; GEFSP1
UNIPROT ID:   Q07699 (Gene Accession – NP_001028 )
Background:    Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction.
Immunogen:    Synthetic peptide of human SCN1B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220882(SCN1B Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220882(Anti-SCN1B Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 220882(Anti-SCN1B Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D262166(Anti-SCN1B Antibody) at dilution 1/35.
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