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SELENOM Rabbit pAb

Anti-SELENOM Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222328

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222328
Product Name:   Anti-SELENOM Rabbit Polyclonal Antibody
Synonyms:   SELM; SEPM
UNIPROT ID:   Q8WWX9 (Gene Accession – NP_536355 )
Background:    The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3′ UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.
Immunogen:    Synthetic peptide of human SELENOM
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 222328(SELENOM Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 222328(Anti-SELENOM Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 222328(Anti-SELENOM Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with synthetic peptide and then with D264401(Anti-SELENOM Antibody) at dilution 1/30.
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