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Semaphorin 4D Rabbit mAb

Anti-Semaphorin 4D Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262881

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262881
Product Name:   Anti-Semaphorin 4D Rabbit Monoclonal Antibody
Synonyms:   CD100; COLL4; SEMAJ; coll-4; C9orf164; M-sema-G
UNIPROT ID:   Q92854
Background:    Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
Immunogen:    A synthetic peptide of human Semaphorin 4D
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R05-2E3
MW:    Calculated MW: 96 kDa; Observed MW: 120 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Semaphorin 4D/CD100 in Jurkat lysates using Semaphorin 4D/CD100 antibody.

Immunocytochemistry analysis of Semaphorin 4D (green) in Jurkat using Semaphorin 4D antibody,and DAPI(blue).
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