Email: info@neweastbio.com   |  Call: 6109452007

SERINC3 Rabbit pAb

Anti-SERINC3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220900

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220900
Product Name:   Anti-SERINC3 Rabbit Polyclonal Antibody
Synonyms:   TDE; TDE1; AIGP1; TMS-1; DIFF33; SBBI99
UNIPROT ID:   Q13530 (Gene Accession – NP_006802 )
Background:    TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis.
Immunogen:    Synthetic peptide of human SERINC3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: Oct-50;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 220900(SERINC3 Antibody) at a dilution of 1/20(Cytoplasm or Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 220900(Anti-SERINC3 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 220900(Anti-SERINC3 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with synthetic peptide and then with D262190(Anti-SERINC3 Antibody) at dilution 1/20.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Human right lung cancer tissue, Human left lung cancer tissue;
Primary antibody: 220900(SERINC3 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 minutes
          Publications